Macrophages

The interior of a specialized white blood cell, or macrophage, is depicted with a number of spherical lysosomes. A lysosome in the foreground is enlarged by an accumulation of a fatty substance called glucocerebroside, characteristic of Gaucher disease. The illustration depicts the introduction of a chemical chaperone into the lysosome that allows the fatty contents of the lysosome to be degraded and eliminated from the lysosome. Courtesy: National Human Genome Research Institute